Priligy (Dapoxetine)

Priligy (Dapoxetine)

Priligy (dapoxetine) is a prescription oral medication used to treat premature ejaculation in adult men 18 to 64 years old. It belongs to a class of drugs called selective serotonin reuptake inhibitors (SSRIs) and works by increasing levels of serotonin in the brain to help control ejaculation. Priligy is approved in some countries but does not have FDA approval for use in the United States.

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Reviewed by Olivia Irving, PhD, On November 6, 2023

As with any medication, it carries certain risks and should only be used under medical supervision with a valid prescription.

Home » Premature Ejaculation » Priligy (Dapoxetine)

Priligy (Dapoxetine): what is it made for?

Numerous medicines were discovered by chance and Priligy is among them. It was intended to cure depression but did not reveal such properties. However, it successfully combats the issue of premature ejaculation (PE). Discover the main prescription features and peculiarities of this medicine.

Premature ejaculation (PE) is one of the most common forms of sexual dysfunction in men. The problem is that ejaculation occurs earlier than we would like, either before or shortly after sexual penetration, bringing a lot of frustration to both partners. This condition depends on a subtle interaction of psychological and emotional factors that can profoundly influence sexual activity. Psychological factors play an important role in PE. This may be early sexual experiences that create memories of rapid ejaculation, or deep anxiety about sexual activity. Men may also experience PE if they had to regularly rush to orgasm during adolescence, which may inadvertently become a habitual response that continues into adulthood.

The main indications for usage

Priligy is the brand name for an active component called dapoxetine. The molecule was created by the scientists of Eli Lilly, while they were looking for new antidepressants. However, it did not work out and was put aside.

Then, it was shown that it could cope with the problem of PE. This fact was backed by science and medicine was introduced into practice. The exact mechanism is still under investigation because it was not clear according to the previous studies.

This medicine is prescribed to solve the problem of PE in adult men from 18 to 64 years old. The following criteria are taken into account before making a decision on its utilization:

  • latency time before ejaculation during the intercourse is less than two minutes;
  • insufficient control over the process of ejaculation;
  • only a little sexual stimulation is required to reach the point of ejaculation, which leads to dissatisfaction between the patient and his partner;
  • severe stress or difficulties in interpersonal relationships due to PE;
  • the onset of early ejaculation in most attempts during the last half a year.

All these criteria should be taken into account. Thus, when the patient is diagnosed with this condition, then he can get this treatment.

However, the problem may be more complex or depend on other medical conditions. Thus, a consultation is required to decide correctly and individually for each patient.

In addition, scientists have been still exploring the possibility of using this remedy for the cure of depression. Thus, it possesses a slight calming effect and may improve the mood.

Dosage and administration

This medicine is sold as pills with two available doses. There are 30 and 60 mg pills.

The usual starting dose for all men is 30 mg. It must be taken from 1 to 3 hours prior to a possible sexual act. In case of insufficient effect and good tolerance of the dose of 30 mg, it can be increased to 60 mg.

The maximum recommended dose frequency is 1 time per 24 hours. Therefore, if the effect was not achieved after the first pill, it’ll be necessary to wait 24 hours before trying again.

Possible adverse effects

The adverse effects are not very common for this remedy. Some patients report headaches and dizziness, nausea, dry mouth, diarrhea and insomnia.

Still, these effects are not severe and usually disappear in a short time without special efforts.

Precautions: who should not use the pills

The main contraindications for this remedy include:

  • hypersensitivity to the main or other components;
  • severe heart disease;
  • moderately pronounced and severe disorders of liver function;
  • severe kidney function disorders;
  • history of established or probable orthostatic hypotension;
  • manias or bipolar disorder.

The medicine is not prescribed for children and teenagers under 18 years of age, as well as for women.

It’s worth mentioning that it does not interact with PDE% inhibitors such as Viagra and others. Thus, these medicines can be taken simultaneously, if there is such a need.

Still, it should not be prescribed together with other antidepressants and medicines that influence the central nervous system to avoid side effects or decrease of the action.


Altogether, Priligy is still a mystery among medicines. Scientists continue to explore its mechanism of action. Nevertheless, the pills are efficient and are able to cope with the issue of early ejaculation and this is evidenced by the clinical practice. In addition, it is possible to purchase them online and solve this pressing issue.


Why do I need Priligy?

These pills are utilized to prevent premature ejaculation in adult men. Usually, they are prescribed by a doctor.

What is the normal dose of Priligy?

There are two available options – 30 and 60 mg. The first one is taken as a starting dose for everyone. Only if it does not work, it is worth moving to a larger dose.

When to take Priligy?

The tablet should be taken from one to three hours before the intercourse. In this case, its efficiency will be the most pronounced.

How long does Priligy last?

Priligy takes effect in 1-2 hours and remains active in the body for up to 3 hours after taking it.

Can I take Priligy daily?

No, Priligy is only approved for on-demand use. Do not take it more than once in 24 hours.

Is Priligy safe?

When used as directed, Priligy is generally safe and well tolerated. But it is not suitable for some patients with certain medical conditions.

Does Priligy cure premature ejaculation?

No, Priligy does not cure premature ejaculation. It provides temporary symptom relief only while active in the body.

Can I drink alcohol while taking Priligy?

No, do not drink alcohol while taking Priligy as it increases the risk of side effects.

Can women take Priligy?

No, Priligy is only approved for use in men ages 18-64 with premature ejaculation.

How much does Priligy cost?

The cost for Priligy varies depending on your location and dosage. On average, it may cost around $15 to $30 per pill.

When does Priligy start working?

Priligy reaches peak effectiveness around 1-2 hours after taking it. Some men respond on the first dose.

Is Priligy addictive?

No, Priligy is not addictive or habit forming when used correctly as prescribed by your doctor.

Priligy (Dapoxetine)