What is Diflucan?
Diflucan is the brand name for the antifungal drug fluconazole. Fluconazole inhibits the formation of fungal cell membranes, thereby stopping the growth of fungal infections. It has now been shown to be highly effective in treating various types of fungal infections, including yeast infections of the mouth, throat, esophagus, lungs, urinary tract, abdomen and vagina. Many studies have shown an effectiveness of more than 80% in the treatment of fungal meningitis and systemic candidiasis. Fluconazole, which is over 30 years old, remains one of the most widely prescribed antifungal drugs.
How to Use
Diflucan comes as tablets and oral suspension. It can be taken with or without food and should be swallowed whole – do not chew or crush them. It may interact with birth control pills, blood thinners, diabetes drugs, rifamycins, seizure medications, and more. Tell your doctor about all medications you are taking before starting fluconazole. Never share this medication with others. Take the full course as prescribed, even if feeling better. Stopping early can lead to recurrent infections and antibiotic resistance. Call your doctor if symptoms worsen or persist longer than one week after finishing the course.
How to Take Diflucan
Fluconazole should be taken once a day at the same time each day to maintain an even level in your bloodstream. Take after a full meal if possible to avoid minor stomach upset. Swallow the tablets whole – do not break, crush, chew or suck on them. Drink a full glass of water to ensure complete swallowing and absorption. If on a longer course, mark your doses on a calendar to avoid missing any. Never take extra tablets to “catch up” after missing one. It is imperative to take the full course as prescribed to prevent recurrent infections and the development of antibiotic-resistant fungi. Call your doctor if symptoms like itching or discharge persist more than one week after the final dose.
How to Take Diflucan
Fluconazole should be taken once a day at the same time each day to maintain an even level in your bloodstream. Take after a full meal if possible to avoid minor stomach upset. Swallow the tablets whole – do not break, crush, chew or suck on them. Drink a full glass of water to ensure complete swallowing and absorption. If on a longer course, mark your doses on a calendar to avoid missing any. Never take extra tablets to “catch up” after missing one. It is imperative to take the full course as prescribed to prevent recurrent infections and the development of antibiotic-resistant fungi. Call your doctor if symptoms like itching or discharge persist more than one week after the final dose.
Dosage
Typical fluconazole dosages are:
- Vaginal yeast infections – single 150mg dose
- Oral/esophageal candidiasis – 100-200mg daily for 2 weeks
- Systemic fungal infections – 100-400mg daily for months depending on type and severity
Higher doses do increase the likelihood of side effects. Always follow prescribed directions.
Side Effects
Most common side effects (occurring in over 1% of patients):
- Headache
- Diarrhea
- Nausea
- Rash
- Vomiting
- Abdominal pain
Less common side effects: Liver toxicity (symptoms may include dark urine, severe stomach pain, nausea, fatigue) Adrenal insufficiency
Heart complications Severe skin reactions (blistering, peeling)
Safety Information
- Do not take Diflucan if you are allergic to fluconazole or similar antifungal drugs or any inactive ingredients.
- Use caution when taking other drugs that affect the liver – combining them with fluconazole increases the risk of liver damage. This includes acetaminophen, certain antibiotics, anti-seizure drugs, cancer medications, and many others.
- Long-term or high-dose fluconazole therapy may result in side effects including:
- Adrenal gland problems
- Serious heart disorders
- Fatal liver damage
- Tell your doctor your full medical history before starting fluconazole, especially liver or kidney problems, heart disease, cancer, adrenal issues, serious skin reactions to other drugs, or any allergies.
- Seek medical help immediately if you develop severe blistering and peeling of skin, hives, seizures, dark urine, yellowed eyes or skin, severe stomach pain, trouble breathing, irregular heart rate, swelling, or other serious symptoms while on fluconazole.
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